George Town is the capital and largest city in the Cayman Islands, located on Grand Cayman. It was named after King George III. As of 2022, th…George Town is the capital and largest city in the Cayman Islands, located on Grand Cayman. It was named after King George III. As of 2022, the city had a population of 40,957, making it the largest city of all the British Overseas Territories.